After installing new RAM (512GB) and increasing some of the CPU power limits, I also may have just killed my boot SSD (SM953 M.2 22110 with PLP) during an overclocked run of Cinebench which black-screened (for a few minutes, I thought I'd killed the CPUs in the manner discussed by the OP, as the system wouldn't boot up via IPMI at all without hard cycling the power supply itself). After getting the system to POST again, the SSD (and Windows Boot Manager) now no longer shows up in the BIOS boot menu. I'll try to see if it's just in a bad state which can be repaired tomorrow, but given the PLP, I would have expected it to be more resilient against that...