I'd be curious to know the noise level of these, specifically the 2U chassis.I use a Supermicro 4U 24 bay, they make a similar 3U 16 bay. Just to show the case, here's one.
UXS Server 3U Supermicro 16 Bay 6Gbps FREENAS Storage X9DRI-LN4F+ Xeon 12 Cores | eBay
Or 2U 12...
SUPERMICRO 2U BAREBONE SERVER X9DRI-LN4F+ REV 1.20 12x Trays Add CPU/Ram/HDD | eBay
Just examples so you can see what they look like, I'm not really recommending those particular systems, though they look fine.
I really like the InWin chassis, but their price point puts them out of budget, heck, it puts them out of the realm of possibility!As previously noted, I've been very happy with my InWin MS08 mini tower; 8x3.5" hot-swap bays, 2x2.5" hot-swap bays, accepts up to mATX boards and uses 1U/FlexATX PSUs. The inbuilt fans aren't the quietest but are far from loud.
I also use the NSC-800 cases and I'm very fond of them, but they don't offer you anything in the way of expandability past mITX.
If you are definitely considering going past 8x3.5" drives and mATX motherboards, I'd look into the rackmount route. InWin also make some perfectly serviceable 2U and 3U rackmount chassis of which I use the IW-RS212-02SC for a backup server with 12x3.5" hotswap bays. They're not quite as solid as the Supermicro chassis, but they're entirely serviceable especially considering the Supermicro chassis cost a fortune in the UK at least (and almost never appear s/h).
If this was the case, I'd go with the Fractal Define R6 (Much nicer looking, IMO, and matches my current desktop setup)While it's not a true hotswap, NZXT H440 was recommended in anther thread.
This is what I have, super quiet. Around CA$500 new but see if you want find a used one.
SC743TQ-865B-SQ | 4U | Chassis | Products | Super Micro Computer, Inc.
Unfortunately, the footprint of the 743, and 745 is near identical to the Rosewill 4U chassis ... I was hoping for smaller. Hmm, still on the lookout. I like the idea of a 2U 12bay, but the notion is that they're inherently LOUD!I thought OP was looking for smaller footprint. I have and really like 743. 745 is almost similar with hot-swap power supplies.