If you don't need any redundancy, you could do a 1-host vSAN via CLI. But 1 SSD will be 'lost' to being a cache drive (should use a higher DWPD type drive (preferably 3-10 DWPD)), and if 1 drive fails, assume you lost everything.
Creating a vSAN Cluster without a vCenter Server | MrVSAN -> use step 2 and 4 to create a 1-node cluster and claim the needed disks.
Personally, unless you want to create a single disk for a VM that's larger than your largest storage device, I'd just go with multiple individual drives w/o raid and spread your VMs or your VM's disks across the multiple drives.
If you want redundancy, I'd suggest to look at a proper hardware raid controller (e.g. LSI or Adaptec solution).