I used to be a StorageCraft partner - it's now ArcServe. It (SPX) was an awesome system, that cost a fortune. I got to bill monthly for it, so I loved it as a partner. If the money is not a concern - in my opinion, it's (was) the best DRaaS (Disaster Recovery as a Service). We could back up everything as often as we like (1min) and fail-over to VM from Bare-metal, in 2ish min (users wouldn't even notice the server redirection). Once the Bare-metal was restored - move the system back from VM, like nothing happened. That was some sexy "Business Continuity" All with deduplication, incremental backups and automated backup testing of local and remote files. My customer base LOVED it. Ransomware news reports, sold it for me. Good times. I'm not sure what the ArcServe team brings or removes from the SPX system though - I was retired before that merger/acquisition. Oh - and they had good swag/food at conferences.
Datto, Azure, etc are other expensive, effective DRaaS options.
For free, today, for Linux servers, I'd probably go with Proxmox Backup Server. It really only handles Debian Linux Bare-metal servers, containers and VMs. It has many of the same features of StorageCraft SPX if combined with a Proxmox Virtual Environment server.
I've also had success with free Duplicati and free/paid Veeam. I've also successfully done things like Rsync, Syncthing, Robocopy, etc.. Even Windows 7 backup works well for Windows PCs (even Win 11). Windows Server backup is actually good too! Honestly every OS has a free, robust solution either backed in, or freely installed with simple CLI cut/paste options. I just like an all-in-one, single pane of glass solution - so I usually go beyond what is simple and offered directly.
I also used to be a Synology partner. They have really picked up their backup game and I really like what they are doing. They have several packages that backup in several different ways. One or more of those packages should meet the needs of almost any SMB/Home Lab. However I find the cost of entry into Synology, along with their new drive certification program, to be less attractive than just rolling your own server.
If I'm not using a DRaaS solution, then I typically like to have local PCs back up to a same OS family type, file server (keeps it simple), that a Hypervisor can access (to bring up, downed systems, while they are repaired).That file server then has it's files backed to another local server (that focuses on server backups), and that other server has it's files synced to a provider, that is located in a different non-local region (for mega disasters).
Today, I'm setting up a TrueNAS system. I've never used it, so for giggles I'm going to dip my toes.