I would never do this. As much as I understand log-structured file system (LSFS) is a journaled file system much like ReFS so you are putting one journal on top of another which is not really effective. Furthermore, according to this page,
Log-Structured File System – StarWind Virtual SAN®- Starwindsoftware.com LSFS was designed to speed up slow spinning arrays that are not capable of handling tough random workloads which is not your case since you have an RAID5 of SSDs that gives you around 25k-30k random IOps for sure.
To my opinion the best configuration in your case would be RAID5 SSD (Write-back/Always Read-Ahead) --> NTFS --> StarWind Image File (without caching). If you don't fit the storage capacity and deduplication is crucial I would start with Windows built-in one (which is offline and sucks compared to inline like SW does but still...).