I have a hyperconverged cluster running fine for 3+ years without a reboot. Now added a separate Hyper-V host with Azure Backup Server doing backups of the cluster over SMB.
What's important is networking speed, and ideally redundant. Go with 25 Gbit+ NICs with RDMA support. Enable priority control, QoS, jumbo frames. I have a bunch of PowerShell scripts to do the setup if you are interested.
You will need several features installed: Datacenter bridging, Multipath IO, File server.
I'd recommend using NTFS over ReFS and avoid deduplication. Recovering data from a failed ReFS volume with deduplication has been a nightmare of mine for the past couple days.