Got a hold of a Sandy Bridge-EP E5 Xeon and updated the BIOS to the latest, 2.5.According to MSI, yes:
(click Compatibility on the left side, their site doesn't support direct linking)
Support For Big Bang-XPower II | Motherboard - The world leader in motherboard design | MSI Global
Requires BIOS 1.4 at minimum. Not sure what BIOS version it's on and I no longer have an LGA2011 CPU to check with.