Single binary minIO is a perfect add on for ZFS filer to create a single node S3 Cloud/Internet share from a ZFS filesystem, much faster, more reliable and safer than for example a NextCloud stack with many files and services or SMB. ZFS gives redundancy, bitrot protection and snaps in single node mode.
You can use several ZFS filer for a multi node setup to improve availability with many disks and high capacity/performance per node.
MinIO multi node per FC/iSCSI, NFS, SMB or similar is indeed quite pointless