It really isn't quite that clear cut. Reorderings from hardware (or rather, the firmware controlling that hardware) can happen and would leave a ZFS in an inconsistent state on a random disconnect. Even when ZFS only ever issued write sequences that as originally ordered were incorruptible. USB...
I have a 4-processor G34 board using 1U heatsinks with random fans blowing at them. It's not thermically stable in summer, aka about now. It isn't very valuable, so I would prefer not to pay 4x $60 on new HSFs. Best I see are the Supermicro HSFs, but you have to pay extra for the G34 clamps...
Are you sure that you aren't better off with one powerful generic graphics card?
You will lose some RAM, but as you say you don't yet know how much RAM you need with the GPU/accelerator.
Either way I don't think you have to worry about PCIe bottlenecks.
If you are in the US this system with 4...
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