One negative aspect of striped arrays when it comes to home media servers is power consumption, an often overlooked factor. In a non–striped array, only the disks containing the media that is accessed needs to spin, not all of them as is the case in a striped array. Depending on the number of disks (and the kind of disks you’re using) in your array, the power saved can be quite significant.
Another advantage of non–striped arrays, particularly in comparison to ZFS pools, is the relative ease and cost effectiveness of expanding storage.