I have a X11SSM-F which is essentially your board with another 4X PCIe connector soldered in. I'm using off the shelf non-ECC DDR4 made by Crucial/Micron with no issues, and with a Skylake Xeon. Note that the maximum supported memory is 64GB.
@Ojref1 Thank you so much for confirming. I was looking at an auction and wasn’t sure to bid. I don’t need another system but the price was really enticing.
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