Ok, had some play time/restless tonight after my Red Hat Satellite 6 training and labs that kept me up late. Hope this provides at least some 'valued' feedback w/ this off the cuff ZoL testing to ESXi 6.0 GA (build 2494585)
High level here is what I did (you can look at screenies to see more detail) First time doing this, I likes my ZFS on Illumos as stated before but figured I'd give it a whirl to check perf/supportability/stability w/in vSphere env as shared/clustered stg protocol and to see if I could derive a sanity checkpoint on your APD NFS woes.
Installed Ubuntu LTS 14.04.2 server (base w/ ssh) in a ESXi ZFS on Linux config (ZoL, this is simply a Linux VM acting as a storage appliance w/ ZFS packages installed)
Enabled ubuntu repo ppa:zfs-native/stable and installed ubuntu-zfs (native kernel space ZFS guts), created zpool, created ZFS filesystem, configured ZoL stoage appliance VM for NFS support to mount to vSphere (ESXi 6.0), mounted up to an ESXi 6.0 host, installed a win10 VM in 9 minutes w/ good throughput (70-80MB/sec and keep in mind this is inception at it's finest right, my AIO config w/ HBA passwd through to Illumos, install ZoL VM that NFS datastore, install ZoL, pass up another vdisk to ZoL stg appliance VM, ZFS on top of that shared out again w/ NFS...you get the idea...long and short AIO, ZFS, w/in ZFS if that doesn't make your head hurt).